Caryophyllene
Caryophyllene
Summary: Some like it spicy! Grab your nearest bud and take a big whiff. If it has a spicy, peppery smell that hits the nose just right – it’s probably caryophyllene.Â
However, this popular terpene has more going for it than its unique spicy smell, it is actually one of the only terpenes to up the ante and activates our endocannabinoid system, giving those spicy strains a cozy quality according to many of its fans.Â
Think of that the next time you smoke. Most strains will usually have some caryophyllene in them!

the 411
- Caryophyllene is highly concentrated in pepper
- Chewing peppercorns may produce calming effects
- Caryophyllene is often found in foods that may reduce inflammation
- Peppery
- Spicy
- Earthy
- Mood
- Relaxation
- Immune System Response
- Pepper
- Spices
- Musk
- Products with a strong peppery aroma
- Look for a lab report with the percentage of caryophyllene listed in the top three terpenes
DO NOT DELETE OR EDIT
SOURCES
- Cannabinoid Type 2 (CB2) Receptors Activation Protects against Oxidative Stress and Neuroinflammation Associated Dopaminergic Neurodegeneration in Rotenone Model of Parkinson’s Disease (nih.gov)
- Molecules | Free Full-Text | Copaiba Oil Suppresses Inflammatory Cytokines in Splenocytes of C57Bl/6 Mice Induced with Experimental Autoimmune Encephalomyelitis (EAE) | HTML (mdpi.com)
- Molecules | Free Full-Text | Copaiba Oil Suppresses Inflammatory Cytokines in Splenocytes of C57Bl/6 Mice Induced with Experimental Autoimmune Encephalomyelitis (EAE) | HTML (mdpi.com)
- The cannabinoid CBâ‚‚ receptor-selective phytocannabinoid beta-caryophyllene exerts analgesic effects in mouse models of inflammatory and neuropathic pain – PubMed (nih.gov)
- β-Caryophyllene ameliorates cisplatin-induced nephrotoxicity in a cannabinoid 2 receptor-dependent manner – ScienceDirect
- β-Caryophyllene Inhibits Dextran Sulfate Sodium-Induced Colitis in Mice through CB2 Receptor Activation and PPARγ Pathway – The American Journal of Pathology (amjpathol.org)
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